What happens when you try to print in Adobe Acrobat?
What is the error message? Do you have XP, Vista, 7, or 8?
Are you selecting a printer to print to or using the print to PDF option?
Click Start and choose Control Panel.
In the Control Panel, choose Printers and Faxes.
Right-click the Adobe PDF printer and choose Set As Default Printer from the context menu.
Close the Control Panel and open the Print dialog box in Acrobat.
Choose your printer from the Name pop-up menu and then click Print.
Are you receiving an error message for activating?
What is the exact error?
Please try the steps to set as Default which is one of the ways to clear that message...
No problem. Take a look here: https://helpx.adobe.com/acrobat/kb/error-pdf-creation-cannot-continue.html
There are multiple solutions available for this issue. Please try each solution in order