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That may be the only chance you get to do so, so I say don't let this opportunity get away make sure you make small talk at first to feel her out to see if she would even be interested in going on a date and then ask her before the night is over for her number and then call and ask her out for a date. Tell her how you have been feeling about her and that you wanted to ask her out for some time. If at the end of the evening Saturday you feel comfortable asking her out then ask her but if she seems preoccupied with the party wait to ask her when you call her.
Yes most definitely ask for her number and if she seems interested go for it and ask her out.