Question

I have a 5 year old spayed cat. She continues to pee all over our furniture, pillows, pet beds...whatever. We have multiple cats in our home as well as dogs. We've had her since she was born (fostered mom and kittens and eventually adopted them). She has been doing this for three or four years. We've had her checked at the vet with urine samples, US, xrays, blood tests..you name it. All appears normal. She does not defecate outside the boxes. We have multiple boxes that are cleaned daily. We have three extra boxes placed around with different types of litter (we've used the same unscented clumping litter her entire life)in cases she prefers something else. She doesn't use them either. We wash everything she pees on with enzyme cleaner and have now had to throw away a piece of upholstered furniture. She drinks lots of water and eats fine. We have also tried anti-anxiety and anti-depressants, to no avail. We are at a point where we are almost ready to have her euthanized.