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Yorkiee 1year old drop in plt count to 36k/ul low glu 37mg/dl amyl 429u/l     lym6.65     mono 2.6 eats a little no shunts found in liver this happenend all at once last friday He seems to be getting sttronger alt 473u/l alkp 543 u/l   do you have any suggestions he is in hospital
XXXXX@XXXXXX.XXX

Submitted: 122 days and 7 hours ago.
Category: Dog
Value: $15
Status: AWAITING CUSTOMER ACTION
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Optional Information

Pet's Sex: Male
Pet's Age: 1

Already Tried:
nothing just Iv

Accepted Answer

Hello. Thanks for writing in. A platelet count that low is certainly dangerous. Low platelet counts (thrombocytopenia) usually occur due to decreased production, increased sequestration (by spleen or liver), increased use or increased destruction. Infectious agents, particularly rickettsial diseases (tick borne infections), are very common. I would have her checked for ehrlichiosis and rocky mountain spotted fever. Immune mediated causes (body reacts against itself) are also very common, and can happen in the bone marrow or in the blood stream. If there was a severe inflammatory disease occurring, she could have developed a condition called disseminated intravascular coagulation (DIC). In this scenerio, the body uses all the platelets to repair damage to the blood vessels due to severe inflammation. An autoimmune profile and coagulation panel should be ran as well. If the coagulation panel is abnormal, I would be concerned about her getting into rat poison as well. All of times, it is difficult to find the inciting factor that caused the thrombocytopenia. For that reason, all cases should be on prednisone, doxycycline and vitamin K. Those medications tend to cover a lot of these disease processes. Please let me know if you have any other questions. Hope this helps.

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Expert: Texas Veterinarian
Pos. Feedback: 99.6 %
Accepts: 
Answered: 7/24/2009

Dog Veterinarian

7 years of clinical veterinary medicine and 17 years experience caring for household pets.

120 days and 6 hours ago.

Reply

He is home not eating properly but he is eating a little His platelet count is in the 70000 range how ever his liver counts are still high every test you suggested we have done He is acting very tired at times but his sugar is ok now The liver test are better but not normal. We have no rats here and we use only traps for mice but MAYBE Thankyou for your time If you have any more thoughts please send them

Posted by Texas Veterinarian 120 days and 6 hours ago.

Info Request

Well. The 70000 platlet count is certainly better. What medications is he on now?

120 days and 5 hours ago.

Reply

he is on denamar 90mg it is a pill and very hard to give to him

Posted by Texas Veterinarian 120 days and 5 hours ago.

Info Request

I am sorry, I am not familiar with that particular brand name. I can't find it on a search either. Is that the correct spelling? Do you know the generic name of the drug?

120 days and 5 hours ago.

Reply

denamarin a liver protective med f-adenosylmethionine 90 mg and filybin a+b(9mg)

Posted by Texas Veterinarian 120 days and 5 hours ago.

Answer

Thanks. I am familiar with this medication. I would strongly consider doxycycline and prednisone. My biggest concern is that this was possibly immune mediated. The prednisone is used to stop that response. Hope this helps.

120 days and 5 hours ago.

Reply

what is the meaning of immune mediated

Posted by Texas Veterinarian 120 days and 5 hours ago.

Answer

Immune mediated means that the body is forming an immune response to itself. In this case, immune mediated thrombocytopenia means that the body's immune system is destroying the platlets. It is a common cause of low platelets.

120 days and 5 hours ago.

Reply

I will suggest to doctors thankyou very much for your time I will let you know how things turn out

Posted by Texas Veterinarian 120 days and 5 hours ago.

Info Request

Your very welcome. Please keep me updated.

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