Dog Veterinarian
10-yrs of experience in small animal practice, advanced training in dentistry and oral surgery
Ok, lets start. There is PU/PD, you are absolutely sure. Urine specific gravity is low, and there is glucose in urine but the blood glucose is normal. We need to investigate the hypercalcemia (high calcium). It is well known that hypercalcemia can cause PU/PD. Elevated serum calcium concentrations lead to excessive production of dilute urine by inhibiting antidiuretic hormone receptors at the level of the distal renal tubules, causing a secondary nephrogenic diabetes insipidus. Reasons for hypercalcemia include granulomatous disease, osteolytic disorders, hyperparathyroidism vitamin D toxicity, Addison's disease, renal failure, neoplasia, hypothermia.You need to remeasure total calcium, ionized calcium, and phosphorus as a start and let me know. Then I can guide you. Also obtain a full body radiographs to check for any lytic bone lesions anywhere in the body.
Dr.B.