Hi,
I know you aren't going to like this answer, but it is the only right answer: You should only taper off the wellbutrin under the direct supervision of a physician. Although you were put on the wellbutrin simply to combat the sexual side effects, it is still altering the biochemistry of your brain. Now that you are taking Pristiq, there is a definite interaction between the two in your brain. Although you may well tolerate the termination of wellbutrin, the change may also set you into a relapse of depression or anxiety which obviously would do you harm. It is not safe to stop on your own, and you should ask this excellent question to your prescribing physician - and only your prescribing physician.
Good luck.
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Doctor
Physician
Pristiq and effexor are essentially different versions of the same compound, but they have different potencies and different bioavailabilities. This is all the more reason to have the medications altered only under direct physician supervision.
Good luck!