Ink System Failure is a generic error that can mean many things, it could be a symptom of a hardware failure, or it could be a false alarm that you can fix my re-initializing the ink system. Try the following reset and see if the error clears. If not, your printer may need serviced or it is usually a better idea to replace due to the low cost of new printers these days.
Press and hold the "*" keyPress the "#" key and release both keys. Display should say "Enter Special Key Combo" Press and release in sequence the "1", "2" and "3"buttonsPress and release the right arrow button until thedisplay says "System Configuration Menu"Press and release the "OK" buttonDisplay should say "Hardware failure status". Ifnot there already, Arrow Key over to "Hardware failure status",Press and release the "OK" button.Display should say "Hardware failure status:Clear. Press OK to clear".Press and release the "OK" Button. Message changesto "Hardware failure status Cleared. Press Cancel to continue".Press and release the "CANCEL" button as manytimes as necessary, so that, either the "Welcome to Photosmart Express" screenappears, or, the "Ink System Failure" screen appears. PLEASE DO NOT TRY TOPRINT AT THIS STAGE.Using the Power Button, turn the unit OFF andunplug the power cable from back of the printer and wall outlet.Wait 30 seconds for the power to get dischargedand then plug the power cable into the wall outlet first and then into the backof the printerTurn the unit on. The printer may display message"USE POWER BUTTON TO SHUTDOWN THE PRINTER" followed by "PRESS OK TO CONTINUE".Press OK. The Printer will start the "ONE TIME INK INITIALIZATION PROCESS".Allow this process to complete and do not interrupt. Once the initializationprocess is complete, the printer will print out a Diagnostic Page.
At this point, either the error will return, or the printer should function again. Hopefully it will resolve your issue. Thank you.
Try unplugging the printer for a couple minutes, then plug it back in and see if you can hold * and press # XXXXX then enter maintanence mode by pushing 1 2 3.
Another reset you could try is to unplug the printer, then press and hold the # XXXXX 6 keys while you plug it back in.