Thanks for your questions and I understand your concerns. The thyroid cancer doesn't have much to do with breast cancer. As previously stated, fat necrosis and eventual calcifications in the tissue sometimes occur and increase over the course of several years in breast with scarring from reduction mammoplasty. With your history of previous biopsy which did not show any cancer, the calcifications are most likely due to the reduction. But because of your strong family history of breast cancer, both you and your doctors have an increased awareness and concern for calcifications because calcifications and feeling a growth can indicate a breast cancer. Both you and your doctors want to monitor your breast more closely and mammograms every year with a scan if any growth is seen is indicated. If your doctor feels that there is increase in a mass or growth in your breast (or if you do) , this also may lead to another biopsy. If fat necrosis and calcifications grow at a significant rate and the fear of you or your doctor leads to the need for frequent biopsies, then this can lead to eventual breast removal and reconstruction. It is probable that the fat necrosis and calcium deposits will eventually stop increasing and when the breast are stable for awhile (several years), then changes in feeling and x-ray will no longer occur and the level of concern will decrease, although yearly exams and mammograms will continue to be necessary