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Hi, Im a boy of 25 years old, and because of high pressure

 
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Customer Question

Hi, I'm a boy of 25 years old, and because of high pressure (160/90) my doctor prescribed me Micardis to help control my BP.

I have taken my Micardis dose (40mg) for the first time today at 2pm. I do realize now that taking it at that time is not a good idea, and I should switch to a 8am intake time. How do I proceed for the change:
Do I simply start taking it a 8am right tomorrow?
Do I skip one day in between to "start anew"?
Do I clock it back, say I take it a 1:30 pm, then 1:00pm, etc until I get to 8am?

Thank you in advance.
JD

 

Optional Information:
Person's Gender: Male
Person's Age: 25

Already Tried:
Been reduced my sodium intake (approx 70% of DV) and started doing 2 hour of bike per day, but only since 5 days ago. Have only started taking med since today

Submitted: 387 days and 15 hours ago.
Category: Pharmacy
Value: CA$15
Status: CLOSED

Accepted Answer

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Expert:  NJPharmacist replied387 days and 15 hours ago.


NJPharmacist : Hello! I am NJPharmacistI will answer your question to the best of my ability!
NJPharmacist : Hi JD how are you? I would say it would be safe to start it at 8am.
Customer :

ok

Customer :

Im a little stressed over this tho.

Customer :

Considering I already took a dose today at 2pm, is it safe to take it immediatly tommorow at 8am?

NJPharmacist : This shouldn't be an issue at all. In school, they taught us generally besides work related stress, BP is generally highest in morning times when awaking.
Customer :

or should I skip a day, or be more progreeive about this

Customer :

I know its better to take it in the morning now

Customer :

Thats why I want to change the time I take it

Customer :

but every bit of information on micardis seem to heavily implie that constant time taking is crucial

NJPharmacist : It is fine. Even at my hospital they sometimes give a stat dose when the patient is admitted at, let's say midnight, and continue it at 98the am.
Customer :

and immediatly changing to 8am right tommorow might not be wuise since it would be ealry since last intake

NJPharmacist : It is, that is correct. However your situation is different.
Customer :

how is that

NJPharmacist : You will be taking it the same time everyday starting tomorrow.
Customer :

yes

NJPharmacist : You are only taking it for one day. Honestly, it won't be too much trouble.
NJPharmacist : One second switching to my PC.
Customer :

ok

NJPharmacist :

Your situation is different, because you haven't been taking the med for too long.

NJPharmacist :

In hospitals, they are very strict about times.

NJPharmacist :

Daily = 9am by me. Bedtime = 2200.

NJPharmacist :

All meds are given around those times. Period. Unless the MD wants a specific dose.

Customer :

so there should be no "spike bucket" effect then?

NJPharmacist :

However, if the patient comes in at let's say 9 pm , the MD may want a dose now, and then start the regular dosing at 9 am also.

NJPharmacist :

Not so much. Especially since it is so close to 8 am. 2 pm isn't to far off.

NJPharmacist :

By all means, if you feel more comfortable dosing 1:30PM, 1 PM, etc. That is fine.

NJPharmacist :

However, from a clinical stand point, the drug isn't even at "steady state" in your body yet, so the quicker the better you change it.

NJPharmacist :

You may even try to take it at 10 AM tomorrow, then 8 am the next day. It really is up to you. But I think whichever way you do decide to go, you will be fine. :)

Customer :

As long as I'm constant about it, right?

NJPharmacist :

Yes very constant.

Customer :

Is it better to take it with food or not? been planning to take it before eating, but just to make sure

NJPharmacist :

Sometimes people miss a dose, it happens. General instructions for those are NEVER double up on a dose, just take it as soon as you remember.

NJPharmacist :

Do you take any other medication?

Customer :

No, but I have tried to inform myself a bit avout this, and the ponly other med I take sometime is ibuprofen because im subject to headaches. As far as I can tell, I should not take motrin, but switch to tynelol if heacache arise. Is that true?

Customer :

sorry for the typoes

Customer :

typpos*

Customer :

typos*

NJPharmacist :

No problem

NJPharmacist :

I was disconnected sorry

NJPharmacist :

You can take Micardis with or without food

NJPharmacist :

If you do take thyroid medication, you shouldn't take this med with food

NJPharmacist :

See how it feels before breakfast, it really doesn't have too much effect on the stomach. Everyone is different though.

NJPharmacist :

It isn't like, for instance Naproxen, that is better to take with food

NJPharmacist :

Are you still in the chat?

Customer :

I see.

Customer :

yes

NJPharmacist :

Just want to make sure I am not having problems

NJPharmacist :

Ah ok good.

NJPharmacist :

Also, how much salt intake are you consuming?

NJPharmacist :

People generally say no more than 2.3 grams of sodium/day

NJPharmacist :

But a little less I think is better. Sodium can raise BP significantly

NJPharmacist :

That is usually the guidelines, 2.3grams a day.

Customer :

before I could go over 250% DV a day. I now keep myself around 65-70%, just above minimum

Customer :

minimum being 1.5 grams

NJPharmacist :

Good. perfect.

NJPharmacist :

Also it may take a little bit for you to see an effect.

Customer :

I have been told 2 months.

Customer :

Being a mathematician, I dont do lot of exercices, and not being able to cook led to more restaurant wic lead to massive salt intake. I have been changing thses two habits for the past week.

NJPharmacist :

You want that BP to come down quite a bit. 160/90 = Stage 2 hypertension. The doctor may want add another drug in the future just in case it doesn't come down fully

NJPharmacist :

It depends, sometimes a month is sufficient.

Customer :

But my schedule is a bit crazy, so thats why I decided to start at 2pm, but now i have been thinking on changing it at 8am, as said before

NJPharmacist :

Yes, I agree, the earlier the better, and always on time.

NJPharmacist :

It isn't going to be terrible if you are off by an hour or two, it will be OK

NJPharmacist :

but always try to remain on schedule.

NJPharmacist :

Let me link you to some other steps you can do to lower your BP

Customer :

more so for 40mg, or does that not matter at all?

NJPharmacist :

Some non drug options

NJPharmacist :

Not so much, the thing with Micardis is that it lasts 24 hours.

NJPharmacist :

Some other blood pressure medication must be dosed twice a day, or three times a day.

NJPharmacist :

See, the problem with those drugs, such as clonidine, is the risk of rebound hypertension

NJPharmacist :

Those who have to be worried about that effect the most.

NJPharmacist :

Clonidine is a very potent dilator. The route it works is different from other medication.

NJPharmacist :

When the body doesn't have clonidine , or a dose is skipped, blood pressure spikes.

NJPharmacist :

Therefore the medication has to be withdrawn very slowly.

Customer :

Same with micardis?

NJPharmacist :

Beta blockers, such as Coreg have this effect, and are usually dosed twice a day.

NJPharmacist :

Most blood pressure medications- Yes, you have to decrease very slowly

NJPharmacist :

But Micardis lasts 24 hours, therefore, a few hours of missing the medication will not be so detrimental

Customer :

okay.

NJPharmacist :

If a patient doesn't have clonidine for a few hours, his/her pressure may skyrockert, because it is so short acting.

NJPharmacist :

Skyrocket*

Customer :

I want to avoid taking any more med thou. Is there anything else appart from exercices and sodium I can do to lower bp?

NJPharmacist :

I have some good hypertension information too, let me see if I can dig it up

NJPharmacist :

Yup I am going to give you some information.

NJPharmacist :

A BP 160/90 , however, needs to be treated promptly with medication.

NJPharmacist :

Are you familiar with Adobe Acrobat reader? AKA PDF files?

Customer :

Shame I have to worry about this at my age. But I had an ecg which pointed to possible infractus, which I din't have, so my doctor think I may have hearth malformation. But unless confirmation I am not relying on this, and i'm going to do whatever I can to lower this BP. I understand that med is needed for thr time being, but I donM't want the situation to get worse.

Customer :

yes, I am.

NJPharmacist :

I am sorry to here about that.

NJPharmacist :

Trust me, I've had stress related BP issues myself , it really stinks. My BP is still high, I really need to make lifestyle changes myself.

NJPharmacist :

Let me fetch this link, then we can discuss it a little bit, how does that sound?

Customer :

sure.

NJPharmacist :

http://www.nhlbi.nih.gov/guidelines/hypertension/jnc7full.pdf

NJPharmacist :

This is the motherload for all blood pressure lowering guidelines

NJPharmacist :

Go to page 26

NJPharmacist :

Read that little chart, and let me know when you are done, so we can discuss

NJPharmacist :

JNC 7 = The guidelines for hypertension

NJPharmacist :

It is what clinicians use as a handbook.

NJPharmacist :

I have a little extra information on those things in the chart I can explain

Customer :

okay give me a sec.

Customer :

done.

NJPharmacist :

So as you can see, it really isn't a myth that alcohol is good for you.

NJPharmacist :

In moderation, it is actually part of the plan to lower BP.

NJPharmacist :

Weight loss, in my opinion, is the most important thing here.

NJPharmacist :

Are you overweight?

Customer :

200 pounds. Never drank alcohol or coffe in my life too, since I dislike coffee semll, and there is too many alcoolics in my family, and I'm kind of a potoman, so I avoid alcohol as prevention.

NJPharmacist :

Wise..

Customer :

overwight is more on restaurant and the fact that I do little exerccise

Customer :

next to none, but changed that recently.

NJPharmacist :

Good.. Yes you will see quite a change.

Customer :

to 2hours bike ( to work actually) per day

NJPharmacist :

If you drink soda, stop drinking it and replace it with water

NJPharmacist :

In school, we were learning about studies being performed about people stopping soda intake.. and I remember one study, patients had lost on average 13 pounds.

Customer :

well i drink a lot of water, like 4-5 liters a day ( thats why I said I'm a bit of a potomane)

Customer :

really.

NJPharmacist :

Ok good, that's awesome.

NJPharmacist :

Yes, insane right?

Customer :

it is.

NJPharmacist :

I used to be a cross country runner myself.. Then as soon I stopped running I gained so much weight.

NJPharmacist :

I drank a LOT of soda in college

NJPharmacist :

Up late.. Grab a red bull.. Or some Pepsi..

NJPharmacist :

It all adds up. I stacked on the pounds nonetheless.

NJPharmacist :

It really does help though. Just that alone is so vital .

Customer :

never had energy drink either, and I don't like sugar or chocolate. It was more aboutch chips and french fries and burger honestly.

NJPharmacist :

You saw the part about the DASH diet right? That is another key element. I know you hear it all the time on television, from doctors etc..

NJPharmacist :

But it is true.. Diet and exercise is very important.

NJPharmacist :

Just by doing those things alone, will drop your BP. If you get to a normal BMI (Body mass index ) you'll see your pressure will come down too. Sodium intake reduction helps a LOT too

Customer :

I see. this pdf is really useful, I should read that tomorrow.

NJPharmacist :

That is the motherload. I don't let my customers down. :)

Customer :

Is there a general source for getting theses studies for the general public?

NJPharmacist :

What about stress management? How are you with stress?

NJPharmacist :

Yes, for the most part I can give you the names of major guidelines

NJPharmacist :

The studies are a little tougher for the general public to find.

Customer :

I read and researcha lot (kind of my job) and informations on nutrition and meds and such seem contradcitory or hard to get sometime

NJPharmacist :

However, the actual "Gold"standards are easy to find

Customer :

stress is usally high, but I menage it well, if it does make sense

NJPharmacist :

ATP III is for cholesterol. GOLD guidelines is for asthma/COPD. JNC 7 ( JNC 8 is coming out this year) is for high BP

NJPharmacist :

You have to manage stress. I can get stressed easily. I work two jobs, late hours. I have to really start putting an exercise plan in motion myself. It helps out a lot.

NJPharmacist :

I've just been exhausted with family issues and work. But for now XBox makes me happy lol...

NJPharmacist :

Also, I've taken on gardening.

NJPharmacist :

Not only do you learn a lot about the plants, but also, the stuff you grow can be awesome health wise.

Customer :

Well I do reasearch in mathematics, economics and cumputer science, teach to high school and do seminar at universities, so my schedule is kinda hectic lol

NJPharmacist :

Last year I grew a lot of lettuce, peas, corn, brussel sprouts..

Customer :

I see.

NJPharmacist :

Computer science is awesome. I've been trying to teach myself Javascript as of late. It is amazing. iOS is where the money seems to be at. So objective C will have to be something I will learn.

NJPharmacist :

Again, these are all things you must enjoy .

NJPharmacist :

They certainly help destress myself. Stress is very detrimental to the body.. So is lack of sleep.

Customer :

I did some apps for a company 3 years ago. I learned C at 14 years old, I should keep myself good a t it, havent practiced since a long time

Customer :

true.

NJPharmacist :

So you have to find a niche, something you really like. You'd be surprised how much it helps.

NJPharmacist :

I always wanted to learn any time C based language, just never had time. My schedule has been easing up a bit, so I've been learning JS for now. I love it. Feels good to learn something.. The sense of accomplish certainly helps.

Customer :

yup.

NJPharmacist :

If you look at that chart ,on page 26, you can see just by lifestyle changes alone, for some people, can change a LOT

Customer :

Thats what I'm going to do. Thank you for your time.

NJPharmacist :

For a baseline pressure of 160/90, it may/may not be affected solely by lifestyle alone. I'd want to see you on Micardis to be honest until you have the pressure come down a bit

NJPharmacist :

Micardis, and the class of medications, are great drugs.

NJPharmacist :

Not too many side effects, lots of mortality/morbidity changing things that are associated with the drugs.

Customer :

I know, I need to accept the fact that I'm taking the meds. I just hope this will settle down and I will be able to drop them in an year or so.

NJPharmacist :

Preserve kidney function, great for Heart failure patients, etc.

NJPharmacist :

And you very well may be able to.

NJPharmacist :

Key things- Weight loss, Sodium reduction, stress reduction.

NJPharmacist :

Work on those, and I promise you, you'll see a difference.

Customer :

okay. Thank you very much.

NJPharmacist :

I know, especially in the US it is hard to eat right. especially when you are on a busy schedule

NJPharmacist :

But once it becomes routine, it is a lot easier.

Customer :

well canada, not very different on that aspect.

NJPharmacist :

Do you need help with anything else friend? Any other questions?

NJPharmacist :

Oh for sure. fast food is an epidemic .

Customer :

no I'm good.

NJPharmacist :

Have I answered all the questions you had?

NJPharmacist :

Great bud. Def read over the JNC-7 guidelines.

Customer :

yes you did. and yes I shall read this.

NJPharmacist :

It has a lot of useful information. In the future, if you need any studies pulled or any other guidelines, shoot me a line .

NJPharmacist :

Great, am happy to help.

NJPharmacist :

If you are satisfied click accept. If you have any last minute questions, be sure to click reply before accepting .

Customer :

no im good. im just gonna copy all this for future references and click accpet thereafter.

NJPharmacist :

I hope you have a great night. And like I said, don't worry too much about the Micardis. One day starting at 8 am tomorrow is fine. It will take about 5 days for that drug to build up completely in your body. So you are fine. :)

NJPharmacist :

Steady state = 5 X Half life of drug ( in this case, micardis is ~ 24 hour duration ) = 5 days

Customer :

okay. Im going to accept now. good night.

NJPharmacist :

You too . I'll be here if you need anything else. Enjoy your night . :)

Expert TypePharmacist
Category: Pharmacy
Pos. Feedback: 98.3 %
Accepts: 113
Answered: 4/29/2012

Experience: Hospital Pharmacist, with solid clinical knowledge.

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