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Hello and welcome. Thank you for requesting me. I'm sorry to hear that your Guinea pig is having this problem. To answer your question about possible causes, there are many. Insufficient vitamin C can cause scurvy, which can lead to weakness in the backend. You can give get supplemental vitamin C - 50 mgs. per day. Some guinea pigs will eat the children's chewables. You can also use the liquid type made for infants. This would be the only potential problem that could be treated at home. Other possibilities include E. Cuniculi, which is a protozoan brain parasite, injury to the spine, a stroke, or a brain tumor. These will all require a vet's help. If you need more information, let me know in a reply. I hope this will turn out to be something treatable. Anna
I will be logging off for the night soon, but will check back n the morning to see if you need anything else.