Thank you for getting back to me. I'm sorry for the delay. There was a glitch in the system that caused me to not receive notification that you had responded to my information request. While it's impossible to be certain based only on an online description, it is probable that this is a fungal infection. Because your other anole died so quickly from this condition, I suspect it is a type called yellow fungus, despite the fact that it's often other colors. It is often quickly fatal.
This fungus is difficult to treat. Some of the best results have been obtained using colloidal silver water and Nolvasan. You can buy Nolvasan in some pet stores, from vets, and online. Dilute it 3 ounces to a gallon of water. It should be kept away from the eyes. You can read more about it here:Nolvasan
Colloidal silver water is available in health food stores. Bathe your anole 2-3 times a day, alternating between the colloidal silver water and the Nolvasan.
You can then rinse your him and coat the affected areas with an antifungal medication - the type women use to treat yeast infections. It would also be helpful to give him some probiotics (beneficial bacteria). Here is an online source:Probiotics
If your anole is eating, add the probiotics, 2 mls. daily of the silver water, and some bee pollen and royal jelly to his food. If he's not eating, mix those supplements into some chicken baby food, and drop a tiny bit at a time onto his snout. Most of the time, they'll lick it off. Don't try to force feed. Here's an online source for the pollen and royal jelly:Pollen
There are two aspects of your husbandry that need to be changed to help him recover. Use a solid substrate, such as ceramic tile or reptile carpet. It's very important that your anoloe be kept clean and dry, and that's much easier with a solid substrate. I am especially concerned that you may not have a UVB light. Full spectrum and UV or UVA are not the same thing, and will, over time lead to a serious health condition called Metabolic Bone Disease. It causes a slow and painful death. It also affects the skin. If your lights don't specifically say UVB, you'll need to get a UVB light as soon as possible. A Reptisun 10.0 is a good brand.
Treatment for yellow fungus has to be long-term; otherwise relapses are likely.
If you have additional questions, just let me know by clicking on REPLY. I hope you're able to clear this up. (Thank you to Joan, for her invaluable tips. Joan has successfully treated yellow fungus using these methods).
(If you find my answer helpful, please click on ACCEPT. Thank you.)
Edited by MsAM on 1/14/2010 at 12:27 AM EST