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Can you tell me when she had blood work done last.
How often is she having seizure like activity?
Any head tilt or raid eye movement?
Is her stomach larger or harder then normal?
Are her gums nice and pink or are they pale or white in color?
You mention she drinks a lot of water, can you tell me if there has been any increase or decrease in her appetite?
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I did not request a phone call. That is generated by the site not me, in fact I do dnot do calls at all.
Panting can be a sign of pain and that combined with the leg weakness could be due to a problem such as slipped,or compressed disc.
Now with large breed dogs one of the problems we see in seniors is a tumor on the spleen. Very often we do not even know that there is a problem until the tumor begins to bleed. Sudden hind end weakness that comes and goes is often a sign of a mild bleed.
Increased drinking can be signs of diabetes, liver disease or a condition called Cushings disease. All of the above can cause seizures.
Due to her age a hands on exam is going to be needed so I agree that having her seen by your vet tomorrow would be best. If she goes down and can not get up, her gums become pale or white in color or she seems to be having trouble breathing then I would have her seen tonight.
I apologize that I can not give you a for sure answer on what is happening here