The are a variety of concerns when we see vomiting and diarrhea in puppies this young. Our first concern should be intestinal parasites even though 2 of the puppies have been dewormed, another concern should be a virus shared between the puppies such as parvo or distemper.
My recommendation would be to either take the whole litter of puppies in to see a vet or hire a mobile vet to come see them within the home, whichever is easiest for you. If this happens to be viral, their best chance at survival will be quickly addressing the symptoms with an effective treatment plan.
Failing this, you can administer a dose of regular pepcid (famotidine) every 12-24 hours to each puppy. You need to weigh each individual, especially if they vary greatly in size. You will want to give 0.5mg/pound of body weight (a 10# ***** would receive 5mg, a 5# ***** would receive 2.5mg, etc). For this, you can visit any human pharmacy and buy the OTC brand name Pepcid, or you can use the cheaper, off-brand “famotidine” that’s available. Either will be useful.
2 hours following a dose of famotidine, the time needed for the medication to begin working, you can offer a bland diet. To make this, you’ll combine white or brown rice, boneless, skinless chicken breast and sufficient water for cooking in a stock pot. Boil on medium until it turns to mush and the breast is easily flaked. To avoid more nausea, start with small amounts to begin with and offer the amount every 2-4 hours. A few teaspoons to start is typically sufficient and you can work your way up every 2-4 hours in incremental increases until you’re sure no vomiting will be seen. If they require a more palatable food, try adding in pureed baby food in chicken, turkey and similar flavors. Avoid those that contain onion or garlic in the ingredient panel. Work up to feeding exclusively until at least 3 days following the resolution of the GI upset. After this, work on slowly switching back to the regular food that they typically eat.
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