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Hi this is Dr. Hill. I need to ask a couple of questions in order to help you with Jello.
How long has the skin lesion been present?
Does she seem itchy?
Do you put use any flea/tick products on her. Is the lesion on the top of neck or underside? Does she wear a collar that could be causing irritation to lesion?
Is there any discharge from the area or is it just hairless?
?Great information. Thank you. The pictures look like there is a raised, hairless nodule that has a rough surface. Is this correct
Okay. That is likely Sebaceous Hyperplasia. Which is basically an overgrowth of sebaceous cells. These are benign and only need to be removed if they become infected (a possibility with the other dog licking) or unsightly. It is very common in some dogs as they age. It can be removed, if infection becomes and issue.
It could also be a sebaceous adenoma, which is also benign.
If it is red or inflamed (hard to tell from picture), then you can use a topical antibacterial cream or oral antibiotics (cephalosporins from local vet). I would not cover because that will not make a significant difference and may make it worse. Yes, they do continue to grow. Many people choose to have them removed. Best to prevent housemate from licking the area because it will introduce bacteria.
They are easily removed with a light sedative and local anesthesia or with general anesthesia.