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I am sorry to hear you are worried about your Beagle. I am a veterinarian and will do my best to help.
It will not hurt him to get 300 mg of doxycycline. If he took it on an empty stomach, he might vomit; doxycycline is irritating to an empty stomach.
Let me know what else I can help with or answer.
She should be fine. Let me know how she is doing and if I can answer anything else.
Kindly consider rating my answer (always appreciated!); you can still get back to me with questions and updates. Rebecca
Those Beagles will eat anything!