Hello, and thanks for writing in.
At home, you can try over the counter plain Benadryl (diphenhydramine) at 1mg per pound of body weight. It commonly causes some degree of drowsiness, and may be enough to get the nail trim done. If it's not enough, you may need to either bring Molly to a groomer or a veterinarian for a nail trim, or get a stronger medication from your veterinarian to bring home and give to Molly to make her more sedated for the nail trim.
I hope this helps.