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CriticalCareVet, Veterinarian
Category: Dog
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Experience:  Emergency and Critical Care Specialist
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My dog has elevated liver enzymes (ALT and SAP). We assumed

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My dog has elevated liver enzymes (ALT and SAP). We assumed this was some kind of poisoning from a Made in China chicken jerky treat we've been feeding her (just found out about this), however she plays a lot with the dog next store whose stools are WHITE. Is there something contagious she may have caught from him that would cause this? She was sick for a few days with diarrhea, vomiting, lethargy, and excessive drinking when this all started. She is acting fine now, but the doctor wants to put her on Amoxicillin and Flagyl. Wondering if there is something else we might be missing.
Submitted: 4 years ago.
Category: Dog
Expert:  CriticalCareVet replied 4 years ago.
Welcome to JustAnswer! I am a licensed veterinarian and would be glad to help!

Possible causes include for these liver value elevations include:

- Hepatocellular injury (injury to the liver cells) / Toxin
- Infection / Inflammation (LINK HERE)
- Neoplasia

There are several ways to proceed:

1) Conservative route - medical therapy and time.

Medications to discuss with your veterinarian would include Denosyl, Denamarin (LINK HERE), or Milk thistle as examples (LINK HERE). This are medications to help the liver.

Yes - I would also agree - some even start medications such as metronidazole and amoxicillin (antibiotics) in case there is an early hepatitis.

Use the medications for several weeks (2-3) and then repeat bloodwork.

If still elevated, and you wanted to be proactive, I would then consider an abdominal ultrasound.

The other option is to get an ultrasound now to further evaluate the liver to see if a more specific cause can be found with this non-invasive test.

Please let me know if this helps clarify this for you.
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