OK, thanks. XXXXX:

Clinical Signs:
> increased drinking
> increased urination
> voracious appetite
> pot-bellied appearance
> panting
> occasional vomiting/ diarrhea

Diagnosis:
> Routine bloodwork- usually shows increased liver enzymes (ALT, ALK phos), dilute urine
> ACTH Stimulation test will give diagnosis
> High Dose Dex suppression or ultrasound of abdomen will tell you if it's due to a tumor in the brain (pituitary adenoma, most common) or adrenal gland (often cancer, less common)

Treatment:
> If pituitary adenoma- treat with Lysodren to destroy the adrenal glands to the point where you're not seeing the clinical signs of Cushing's. There are many side effects and frequent rechecks are needed while initiating therapy to prevent excessive destruction of the adrenals.
> Trilostane is the other medication that may have less side effects but is not as effective.
> Surgical removal of adrenal tumor if present

Prognosis:
> WIth Lysodren the average lifespan after initiating treatment is 2-3 years
> With benign adrenal tumor after removal- excellent
> With malignant adrenal tumor- guarded

Hope that helps, let me know if you have any more questions.