I'm guessing that the Genesis you used is a topical spray by Virbac containing 0.015% triamcinolone acetonide. If this is not correct, please tell me what it is. I'm assuming it is not the laser treatment called Genesis.
I would be very concerned about a dog that had not eaten for 3 days, is not drinking and is non-responsive. These are not signs associated with hot spots (pyotraumatic dermatitis). It sounds more like a systemic infection or other problem.
Can you get a temperature? A human thermometer lubricated with vaseline , K-Y jelly or water is OK. Gently insert it 2-3 inches into the rectum and leave it for one minute. Normal temperature for dogs is 101 - 102.5 F. 103 is a low grade fever. 104-106 is a common fever range in dogs. Less than 100 is hypothermic If she is hypothermic, get her warm with blankets. Hot water bottles (gallon jugs filled with hot water) help. Heating pads tend to get too hot and burn.
Look at her gums (mucous membranes). They should be pink, not white, gray or deep red. Check her capillary refill time by pressing a finger over her gums behind her upper canine tooth. It should be pale when you remove your finger and return to pink within 2 seconds. 3 seconds or longer indicates dehydration.
Try to get her to eat and drink. Offer anything good (chicken, tuna, cat food, water, soup).
Do you have any antibiotic ointment (Neosporin, triple antibiotic, etc.)? If so use it on the hot spot.Stop the Genesis.
Do you have any antibiotics for dogs?
Could she have gotten into anything toxic?
Let me know if you have follow up questions.