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Hi,Normal disinfection and cleaning will kill the distemper virus. Normal disinfectants and cleaners kill distemper, so disinfecting carpet cleaner should do the job on carpets and sofas. It also does not live that long in the environment and is usually gone in a few weeks. You can read about it here: http://www.veterinarypartner.com/Content.plx?P=A&A=1733I suggest cleaning everything down well with a bleach solution (1 part bleach to 30 parts water). This should disinfect it well enough to prevent infection of a new puppy.I hope this information is helpful to you.