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Hello, I'm Dr. Deb and will do my best to help you today.
If you're just double checking about any contraindications about giving Depo Medrol subcutaneously (SQ) versus intramuscularly (IM), then there aren't any. I've given this drug SQ for years with no issues. It appears to be well absorbed this way and cats don't appear to be as uncomfortable as when it's given in the muscle.
I'm sure your vet has cautioned you about the chronic use of steroids of any sort since patients may be at risk for developing diabetes but I did want to at least mention it if they hadn't.
I'm also certain that you've increased water consumption, tried to reduce stress (Feliway is sometimes helpful in this respect) and/or possibly started Cosequin for Cats which may help in some of these patients.
I hope this helps. Deb