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to better assist you , can you answer the following questions?
How long has she started this now?
is it looking the same as when it started?
Any concurrent illnesses?
Any change in water intake lately?
Any change in urination volume?
Any contact with any toxins?
Does she still has her URI?
Do you mean by FSE Feline Ischemic Encephalopathy?
Let me know, looking forward to assist you.
the symptoms you are describing can be from many diseases:
Feline infectious peritonitis Toxoplasmosis Brain neoplasia
FSE has been documented in a few domestic cats in Switzerland, Liechtenstein, and Norway and in several big cats (puma, tiger and lion) in zoos in various European countries. It is thought that the disease was contracted by eating food containing animal brain tissue or bone marrow that was raw or insufficiently heated.
Clinical signs consist of behavioral changes (aggression, biting, scratching when stroked, hiding, vacant staring, excessive grooming, easily startled), cerebellar signs (ataxia, hypermetria, intention tremors of head), muscle tremors, pelvic limb ataxia or weakness).
A study was conducted to check for possible FSE in Europe on about a 100 cats with fatal neurological symptoms and the follwoing were found: neoplasia (21.8%), toxic-metabolic encephalopathy (18.2%), granulomatous encephalitis (15.5%), suppurative encephalitis (4.6%), trauma (3.6%), circulatory disorders (3.6%), degeneration (2.7%), nonsuppurative encephalitis (2.7%), and neuromuscular diseases (1.8%).
In your case, unfortunately, unless you are in Europe right now, other diagnostic tests would need to be perform to know for sure what is the problem. If all basic blood work, urine analysis, blood pressure, sinus radiographs, FeLV and FIV negative, an MRI and a SCF tap would be indicated. I know you mention a tight budget, if all else fails, you can discus with your primary care veterinarian to try some steroids, or treat for toxoplasmosis. Due to the progressive nature of the problem, a brain tumor is very high on my list. this will not be able to be cured unless you have surgery, or could be helped with radiotherapy. FIP cases all die, even if you try to treat.
it is sad to say, but you may have to think about putting him down. I am sorry.
Let me know if you have more questions, or need additional information.
if this helped answer your questions, do not forget to select the ACCEPT button.
yes, blood work will be normal in some of those conditions. FIP and toxoplasmosis would likely have some elevated white blood cells, elevated protein.
Good luck, keep me posted.
I have 3 and a dog :-)
Protein appears a little high, but I do not have the normal range in front of me. The albumin is a little high which could be from dehydration.
As to ask for me in the future:
You can send me a private message, then open the question with my name on it when I tell you I am online.
I am on pretty often, but know that I will be off for several days after feb 4th.
Hi, I like Julian, it is beautiful, i've passed by several times.
we can't tell clients where we practice. But I should be around on line for a while :-)
one you want to think about when you have a lot of cats around is FIP, it can attack the nervous system:
From the same site you found (I use that one a lot):
One of my favorite site.
impressive! Do not know how much she will come back to, but awesome job. You are great owners, you went for it, and tried to find out what was going on.
Good luck, and hang in there!
I'll give you a short answer tonight, and will look it up more tomorrow.
did the test was IgG and IgM?
What is the weight of this little one?
Some people do have success in treating with 25 mg twice to 3 times daily. The thing with eh clindamycin, it tends to give diarrhea easily, and doing a low dose may be more helpful to decrease those side effects. the other drugs used to eradicate the toxo tends to have too many side effects o be used.
Treatment would be a minimum of 6 weeks, and probably in neurological disease you may be looking at 8-12 weeks. Prognosis is usually guarded in neurological symptoms.
The odds of complete recovery depends on the site and extent of the infection and how much residual scarring will result. Many cats do recover completely, some will retain residual deficits. Occasionally seizures occur as a long term complication but these can generally be controlled with anticonvulsants. Neurological form very hard to get rid of.
The Clindamycin does not eliminate the toxo, it does make it dormant, and relapses are possible.
I have not seen any reports of problems after treating with clindamycin on the veterinary boards. Did you get those datas form human toxo cases?
you can have pneumonia with toxoplasmosis, and i would not think kidney failure in cats with toxo.
Let me know where you took those datas from.
One thing if she is not responding, cryptococcus is another one to add to your list.
Let's see how she responds.
Let me know
make sure you discuss the dose with your primary care veterinarian, they may have a reasons to keep it so low, and it might be from her general condition. You do not want to go too high since this medication, she will have to be on it a long time. i am sure your veterinarian will renew the prescription when needed.
Cats will improve dramatically within 24-48 hours. If her optical nerve is inflamed and she ha no permanent damage, you may see some improvements in one week from now.
Treatment is usually done up to 2 weeks after the disappearance of the symptoms. In her case it might be until you have no more improvements. Let your veterinarian discuss this with you. As for references, they come from various source, but I like to look on my veterinary boards and look at others experience (sometimes better then reading a book, they have a lot of specialist answering veterinarian's questions), Plumb's which is a medication bible for veterinarians, and the 5 minute veterinary consult canines and felines, Infectious diseases of the cat and the dog..
As for cryptococcus, they can have a single lesion not apparent.
Hi Chuck, keep me posted!
Happy to hear Chelsea is still making progress.
As for the Clindamycin, I am not sure about the formulation you have, The one that comes formulated for dogs and cats, has a long shelf life and is not reconstituted. So , best is to see the expiration date written on the bottle (you should have one). If you do not see one, call the pharmacist. I would recommend treating with the Clindamycin up to 2 weeks after all improvements have ceased. If the Neopectate is helping the stools consistency, I think it is a good idea to continue it.
Awesome news!!!!Keep going. Thank you for the update.
Another kitty! Hope he does well. Yes, more people will abandon their animals due to the economy unfortunately.
nice to hear from you!
Sorry to hear that Chelsea is now on a plateau. But this is to expect with toxo. You treat and whatever is left as brain damage you will probably not recover. As regression, it is hard to know if there is a relapse or not. You can always put Chelsea back on the Clindamycin, run titers. AIDS patient positive for Toxo do relapse and will need medication again.
You may discuss with your primary care veterinarian putting Chelsea on Clindamycin when she relapses for 2 weeks. There also is a possibility something else is going on like a brain tumor too.
I would make sure she has a good quality of life. Brain damage could potentially improve the first 6 months, then that is the way she will stay. If there is no improvements at this stage, I do not expect much more improvements.
Feral cats, some do get more social, but most do not. Patience, patience.....
Good luck, and keep me posted.
long time, no news!
Glad to hear about Chelsea.
Is the lump under the skin or on the skin?
How big are they?
Hi hard to tell what the lump could be. Might be able to do a fine needle biopsy. Should not be part of toxoplasmosis however, could have some fungus in there, or other type of organism. Crytptococcus could be possible (fungal). A fine needle aspirate, or surgical excision if the mass is too firm (might need radiographs) might be necessary!
Keep me posted!
Thanks for the kind words as usual
Life is good here and the kittys are doing well.
Nice to hear form you, Nancy and the zoo!
Hope you're all well. And looks like the old lady Chelsea has her way of communicating. She is smart!
Keep me posted,
thank you for the update, hard to tell what the nodules were about without a fine needle aspirate or biopsy.
I am sure your help maintained her as much as you possible.
She is quite a tough kitty, but all good things have an end, so ending her life at this point will be best as you decided.
Thank you for letting me help you and good luck with the whole gang!
Don't make me cry now...
Hang in there with the rest of the gang.
I'll close this question after this.
Thank you for letting me help you with Chelsea.