I will try the antihistimine in the morning. Yes, the Cefa is less than 14 days. I had my other cat in just last week. So I will stick with it. I plan on rinsing everything in bleach water in the morning since I understand this is a pesky bacteria. Menace just came down stairs and wandered around and let me pet and hold him so maybe he is feeling a shade better. I will definitely have him at the vet Monday as he has a 10 am appointment. Right now he is still having a wheezing cough but it not all the time. He sounds like he has a stuffed sinus sounds in humans. Thanks for the quick help I mostly wanted to make sure he was not in dire straits until monday. I will watch him closely. I have 3 cats and a dog. So I have a full house. Menace's brother ( Phantom) who had this as a kitten has shown no signs of infection so I have my fingers crossed. He and his brother were abandoned by their mother in my yard two years ago and were so little there eyes were still blue. I bottle fed and weaned them both so as you can imagine they are my "kids".