How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Elena Marie Your Own Question
Elena Marie
Elena Marie, Cat Rescuer and Caregiver
Category: Cat
Satisfied Customers: 155
Experience:  Cat Owner, Rescuer, and Caregiver to Many Chronically Ill Cats
15822
Type Your Cat Question Here...
Elena Marie is online now
A new question is answered every 9 seconds

what are the prognosis of cholangial hepatitis in a 12 year old cat

Customer Question

my cat was diagnosed this today after blood work was done yesterday with cholangial hepatitis.. I was unsure of what we should do until the Dr. phoned us. He said that there is meds he can put her on. I agreed to do that I know she is elderly but, I would like to try and see if this may turn around. what would cause this and what is the chances of the medication working. she is jaundice now and only 6lbs. He also is going to give her more med for her throid. She is playful this morning and has eaten 2 small cans of fancy feast turkey and giblets... please let me know what I am dealing with..
Submitted: 11 years ago.
Category: Cat
Expert:  Elena Marie replied 11 years ago.

The following is from the website below:


http://www.vetinfo.com/cchohep.html#Cholagiohepatitis


Cholagiohepatitis

Q: Our cat is 2 1/2 years old and eats a little here and there - some times vomits (4 x month) and is quite thin - male cat. I rarely see him drink water. He had two ticks we removed from his neck area last year ( I am not sure this means anything). His bilirubin is 1.7, I understand normal is .5. His other liver function tests where elevated as well. He was diagnosed with choliangiohepatitis. What is this disease and is it preventable? The cat is now taking DAP.

A: Patricia- Cholangiohepatitis is a descriptive term for inflammation of the bile ducts and subsequent damage to the liver. Cholangitis (bile duct inflammation or infection) can occur without liver damage but due to the importance of the bile ducts to liver function there is usually a secondary hepatitis There are actually several causes of this condition in cats but they fall into three broad categories --

1) suppurative (usually bacterial infection) cholangitis/cholangiohepatitis

2) chronic lymphocytic cholangitis/cholangiohepatitis

3) lots of other primary diseases that can lead to secondary cholangiohepatitis or cause it as part of the overall disease process. These include toxoplasmosis, Tyzzer's disease, Hepatozoon protozoal infections, kidney failure and possibly immune mediated disease.

Suppurative cholangiohepatitis is probably the result of infectious agents such as E. coli invading the bile ducts from the digestive tract. Since this isn't a common occurrence it is possible that the body's natural defense mechanisms may be deficient in some way or that some pre-existing liver disease may be present making infection easier. This form of cholangiohepatitis usually has fever, inappetance, weight loss, depression, and sometimes jaundice associated with it. It is less likely to be an intermittent problem than lymphocytic cholangiohepatitis.

Chronic lymphocytic cholangiohepatitis causes weightloss, may cause an increase in appetite or less commonly a decrease in appetite, weight loss, fever, ascites (fluid accumulation in the abdomen), jaundice and sometimes neurologic signs. It is often an intermittent problem with a "waxing and waning" course.

Obviously, the signs of these disorders overlap since the damage that occurs is similar. It is probably impossible to tell them apart without a liver biopsy. Bloodwork, including checking liver values and white blood cell counts helps to identify the presence of cholangiohepatitis. Liver biopsy makes it possible to tell which type is present. In some instances biopsy of the liver doesn't look like a good idea after doing the labwork.

If suppurative cholangiohepatitis is present it is necessary to treat with antibiotics to control the infectious agent. It may take several months of antibiotics to eliminate the infection. At the same time it is necessary to support the liver function. If inappetance is present, using appetite stimulants may be necessary. Dehydrocholic acid (Decholin Rx) is used in cholangiohepatitis to help control the inflammation. Surgery may be necessary to correct bile duct obstruction in some patients.

If the diagnosis is chronic lymphocytic cholangiohepatitis it may be responsive to prednisone or other corticosteroids. Since the use of cortisones could be a problem if infectious agents are present it is pretty important to rule out suppurative cholangiohepatitis prior to using prednisone, if possible. If ascites is severe enough, diuretics may be necessary to control it or even drainage of the accumulated fluid (this must be done cautiously). Supportive care is necessary for this type of cholangiohepatitis as well.

Mike Richards, DVM

Hope this information might be of help.


God bless and good luck!



JustAnswer in the News:

 
 
 
Ask-a-doc Web sites: If you've got a quick question, you can try to get an answer from sites that say they have various specialists on hand to give quick answers... Justanswer.com.
JustAnswer.com...has seen a spike since October in legal questions from readers about layoffs, unemployment and severance.
Web sites like justanswer.com/legal
...leave nothing to chance.
Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood pressure, drinking and heart pain jumped 33 percent.
Tory Johnson, GMA Workplace Contributor, discusses work-from-home jobs, such as JustAnswer in which verified Experts answer people’s questions.
I will tell you that...the things you have to go through to be an Expert are quite rigorous.
 
 
 

What Customers are Saying:

 
 
 
  • The response from the Expert literally saved my cat's life. Thank you from the bottom of my heart -- I will recommend all of my friends to you!!! Lucia Rincon, Georgia
< Previous | Next >
  • The response from the Expert literally saved my cat's life. Thank you from the bottom of my heart -- I will recommend all of my friends to you!!! Lucia Rincon, Georgia
  • I will use your service again. I was very pleased with the response and the fact that you have a low cost option so that those of us on fixed income can have questions answered. I will also recommend you to others. Karen Jackson Heights, NY
  • You helped us to come to what we believe is a better next step in Jack's treatment, and hopefully have saved us $800!! Thanks again! Jack's Mom Tuscon, AZ
  • The vet said that the information and my following it will be what made the difference. Thanks again for being so very helpful. Tracy Grayson, LA
  • My oldest male cat had a seizure this evening. This site was the first place I could think of to go after the seizure had passed. Dr. Lucy was fantastic and she was spot on! Debbie USA
  • I must tell you I found this site by accident and was amazed when I asked a question of the Veteranians online. I wish I could have found it sooner it could have made such a difference in the outcome of my pet's surgery. However, I am passing along the information to my sister-in-law (a cat-rescue person who is also a nurse), and perhaps it will help someone else who may experience the same problem. The doctor who answered my question was amazing, and while it didn't come it time to change the outcome of my situation, it is reassuring to know the caliber of Vets/Doctors that you have at JustAnswer. Thank you for being there. Alice H. Jacksonville, Fl.
  • Wonderful service, prompt, efficient, and accurate. Couldn't have asked for more. I cannot thank you enough for your help. Mary C. Freshfield, Liverpool, UK
 
 
 

Meet The Experts:

 
 
 
  • Terri

    Terri

    Feline Healthcare Expert

    Satisfied Customers:

    20381
    Expert in feline health and behavior. 20 years experience with cats.
< Last | Next >
  • http://ww2.justanswer.com/uploads/purrfectkitty/2008-07-10_084515_2006-06-10_me2.jpg Terri's Avatar

    Terri

    Feline Healthcare Expert

    Satisfied Customers:

    20381
    Expert in feline health and behavior. 20 years experience with cats.
  • http://ww2.justanswer.com/uploads/RY/rydergar/2012-6-6_192240_IMG0328.64x64.JPG Dr. Gary's Avatar

    Dr. Gary

    Cat Veterinarian

    Satisfied Customers:

    966
    DVM, Emergency Veterinarian; BS (Physiology) Michigan State Univ
  • http://ww2.justanswer.com/uploads/CE/Cerecita/2011-3-16_2565_JAPIC500x500.64x64.jpg Cher's Avatar

    Cher

    Feline Specialist

    Satisfied Customers:

    10545
    Feline Healthcare & Behavior Specialist 40+ years Experience
  • http://ww2.justanswer.com/uploads/kydoll/2008-11-26_190500_me.jpg Lori's Avatar

    Lori

    Feline Healthcare

    Satisfied Customers:

    3325
    16 yrs health care mgmt & issues relating to cats, reproductive issues and multicat environments
  • http://ww2.justanswer.com/uploads/mccprn/2009-11-20_185102_JA_profile.jpg Micki's Avatar

    Micki

    Expert in cat behavior and health

    Satisfied Customers:

    3153
    Expert in cat medical and behavior issues.
  • http://ww2.justanswer.com/uploads/ER/ERPetNurse/2011-11-7_1293_b.64x64.jpg Candy R.'s Avatar

    Candy R.

    Veterinary Technician

    Satisfied Customers:

    3128
    Practicing Veterinary Technician for 26 years.Former Veterinary Practice Owner, Technician Trainer
  • http://ww2.justanswer.com/uploads/BA/babybloo/2011-3-10_62613_DavidandI.64x64.jpg Theresa's Avatar

    Theresa

    A Voice for your Pet

    Satisfied Customers:

    2125
    19+ years in animal medicine as a veterinary technician