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A collection of fluid around the liver (perihepatic fluid) is not specific for any one condition and can be due to a wide number of causes. The fluid could be ascites (an excess of abdominal cavity fluid), blood, urine, chyle (lymphatic system fluid), bile (digestive secretion produced by the liver and stored in the adjacent gallbladder), pancreatic juice (digestive secretion from the pancreas), or pus. With all of these fluid sources, the list of causes may include tumor, obstruction (e.g., bile duct blockage by a gallstone), trauma, autoimmune disease, heart failure, infection, abscess, medication (e.g., Tylenol overdose) or toxin, cirrhosis (liver scarring with dysfunction or failure), etc. Unfortunately, the symptoms you report (headache, ear ache, sore throat, swollen glands, fever, nausea, vomiting, weakness, and loss of appetite) are also nonspecific with countless possible causes. Your doctor and/or one or more specialists (e.g., gastroenterologist, or digestive system specialist) will obtain appropriate labs and imaging studies to confirm the underlying diagnosis for the perihepatic fluid.
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