Treatment of depression is more of an art by trail and error than a pure science because every person is different. That is why there are so many antidepressants on the market. Sometimes if you up the dosage (up to a limit) then it will kick in. Most antidepressant don't start to work right away, but only after a few weeks. Too much antidepressant medication, or mixing more than one, can cause serious side effects. It is very important that once you start an antidepressant that you don't quit abruptly or you can get serious symptoms, even if you are replacing one with another. Most antidepressants have side effects, so you must be on the alert for them, and know what they may be. Therapy is often recommended in conjunction with antidepressants. Sometimes other drugs are added (such as antipsychotics or amphetamines). More drugs mean more risks. I am sorry to hear that your son is one of those people who is resistant to antidepressants. I understand that you have experience with some medications that you didn't mention. Let me tell you what I know about, just in case it is new information to you, in the hope that you will find something. Evidently, your body adjusts to these doses and the drugs thus far have lost effect. Every person is different, and that is what they seem to experiment so much with different combinations and doses. There are the drugs of the MAOI class on your list. (Monoamine Oxide Inhibitors). Such drugs would include tranylcypromine and phenelzine sulfate, and they are often prescribed as a last resort because they can have dangerous side effects and cannot be mixed with certain foods (aged cheeses, pickles, wine) and some other medications, such as some decongestants. A newer, very promising MAOI is worn as a skin patch and has fewer side effects; it is called selegiline HCl. Another very new drug, given by the brand name isXXXXX has promising results and you may want to inform you physician if s(he) doesn't know about it. Another new antidepressant is agomelatine, which has no apparent side effects and has had some very positive anecdotal feedback. Electroconvulsive therapy (ECT) may be offered to you. It passes electrical currents (small) through the brain, affecting neurotransmitter levels. It usually offers immediate relief of severe depression and is used on individuals who don't respond to medications, and also to those who cannot take the strong effects of the medications, such as pregnant women and the elderly. It can, however, cause short term memory loss.
Another option is the implantation of a micro-pulse generator that stimulates the vagus nerve to affect the brain's mood centers. This is yet another way of treating chronic depression that is resistant to treatment. This does not put you at the same risk as ECT, and is a viable alternative. Finally, there is Transcranial Magnetic Stimulation, using electromagnets held against your upper forehead to produce an electric current in your brain for the purpose of affecting those same mood centers. This also does not shock your brain. You have an array of options to consider and balance the costs in your money, time, and other considerations, against the history of failed drug treatment. I sincerely XXXXX XXXXX have been of assistance to you. If this is enough information to get you motivated and give you some hopeful options, then I wish you the very best. Warm regards, Elliott
To let you know,
our son told me he was not taking his Rx because he didn't like how it made him feel, I accept and understand that.
I was done trying. Simply that. I made it clear that he had to wake up, jump out of bed, work a full day, find a job, or I was putting him out and I don't give a damn for his consequences. I told him that if he wants to go commit suicide, to go do it, hang himself, drive into a canal,use a gun, fine with me, and that there is nothing I can't take except watching him continue as he has been doing.
I also said, and meant, that anybody who does not value life enough or is too stupid to treasure every breath they take, should go die and the sooner the better because they don't deserve the precious gift of life. To me, its a case of good riddance of stupid rubbish and we are over populated anyway.
I also said that if he wants a war, he came to the right mother for it, that I no longer trust him and that I shall never in my life forgive nor forget that he told me to shut up. He lost me with that.
Since that next day, Andrew has been working, been polite and tried to make up with a plate of bacon he cooked for me, ( no I did not eat it ) but I sent him to the store for tomatoes, and fresh lettuce. I called him to wake up and he didn't get up so I got a large glass full of crushed ice and water and threw it on his head. I told him that I would never call him more than once . Since that day he jumps out of bed when I call him in the morning.
He went to register for Miami Dade College GED class to start at the end of the month when his brother leaves back to his base so it seems that he does not want to be put out and go to the homeless shelter after all. I would send him to the Peace Corps, if I could, to get into the real world. I think its way past time for me to continue to be worried about anybody else, had enough of that for my lifetime, now, its time for them to worry about me for a change. I have been pushed to the point in my lift that I find I really don't care which way it goes, only that it goes.
Yesterday he came to tell me that he got all of the leaves off the front yard, and cleaned outside, that he was sort of ''proud'' because it actually looks really nice.
In the days before all these wonderful drugs we are doping our kids with, they either worked or they didn't eat. I prefer to keep it that simple. No more pizza, no money in his bank account, no gas card for his car, and you get the idea. The truth is, surprisingly to me too, I actually don't care if he leaves or stays but I will not permit him to stay without earning his keep. He's a smart kid, I think he knows , I have played enough games, now, game over.
I feel at peace more than in so long, I am not drinking any more, and I sleep at night without it. I am doing what I really want to do finally about this, what I know needs to be done.