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Dr. David
Dr. David, Doctor (MD)
Category: Oncology
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Experience:  Experienced Oncology Physician trained in New York City. I'm ready to help.
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What is the differential diagnosis following test results? *

Customer Question

What is the differential diagnosis for the following test results?
* Positive ANA
* Negative DNA (DA) antibody
* Negative SM antibody
* Positive SM/RNP antibody
* Negative RNP antibody
* Negative chromatin (nucleosomal) antibody
* Normal SED rate
Submitted: 3 months ago.
Category: Oncology
Expert:  Dr. David replied 3 months ago.

This is Dr. David

A positive result for RNP antibodies is consistent with connective tissue disease.

when dsDNA antibodies and Sm antibodies are not detectable, a positive result for RNP antibodies is consistent with the diagnosis of mixed connective tissue disease

have you talked to you a rheumatology doctor about the possibility to have mixed connective tissue disease?