How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Dr. David Your Own Question
Dr. David
Dr. David, Doctor (MD)
Category: Oncology
Satisfied Customers: 42782
Experience:  Experienced Oncology Physician trained in New York City. I'm ready to help.
41363181
Type Your Oncology Question Here...
Dr. David is online now
A new question is answered every 9 seconds

My wife is a 68 y/o with squamous cell breast cancer that

Customer Question

Hello,
My wife is a 68 y/o with squamous cell breast cancer that presents as a primary lesion, grade 3, Ki ~67%. HER1 & HER2 - negative. She has no family h/o breast cancer. Her history is remarkable for late pregnancy, obesity,& sedentary life style. I know the prognosis is poor & that the cancer is rare. But, do you have any experience with EGFR inhibitors? And do they have have any significant benefit as an adjunct with chemo for this type of cancer?
Submitted: 10 months ago.
Category: Oncology
Expert:  Dr. David replied 10 months ago.

This is Dr. David

EGFR testing usually is done for adenocarcinomas of the lung, and can be more positive in women who are non smokers and are from Japan or asia

her doctors can test for EGFR mutation in the breast cancer specimen, but most likely it will be negative.

was the breast squamous cell cancer ER negative? or ER positive?

did she have a mastectomy or lumpectomy? any cancer spread to lymph nodes? how large was her primary lesion?

squamous cell cancer is not resistant to chemotherapy. chemotherapy should decrease chances for systemic recurrence.

let me know if you have questions.

Related Oncology Questions