Hi, thank you for contacting JustAnswer.com. My name is Russell. I will do my best to provide the right answer to your question.
To clarify that error message, first of all: it means, "either the scanner is Off, OR the USB cable connection isn't there."
It's possible that you simply have a USB cable that is defective or has gone bad. And make sure it is plugged in at both ends (and switch it to a different USB port on your computer.)
To clarify: This is JustAnswer.com. We do provide advice for Canon products, but are not an affiliate in any way to Canon.
If the scanner was recently purchased and re-seating the USB cable at both ends, trying a new/different USB port, and trying a different USB cable, all don't change the error message, then you should indeed return it promptly to the vendor or store for a refund or an exchange for another... if the return-exchange period of your vendor or store has not expired already.
If it has expired already, then you may require Canon to fix the problem for free, under warranty terms.