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The ultrasound at 12 weeks has an error margin of plus/minus 4 days.
The MoM for free Beta hCG should be 1.0 in women carrying normal fetuses. In women carrying fetuses with trisomy 21 (Down's syndrome), theMoM is usually more than 2.0 and in trisomy 18, it is very less - around 0.18. In trisomy 13, it is it is less than 0.5. On the whole a MoM more than 2.0 and less than 0.5 is considered abnormal and merits further investigations.
Where Papp-A is considered, it is significantly reduced in the blood of women carrying fetuses with Down syndrome and Trisomy 18: the median MoMs are 0.44 and 0.32, respectively (compared to 1.0 for unaffected fetuses).
The Nuchal thickness is the most important ultrasound marker and the most influential on risk calculation. The thicker the NT, the worse the foetal prognosis. Pathological values of NT usually range between 1.8 - 2 MoM or a measure greater than 3 mm (regardless of the MoM). At a CRL length of 70 mm, the normal NT should be between 0.9 to 2.5 with an average of 1.82.
Considering the above data, your NT is within normal range, but the PaPP-A is low. And your free Beta HCG , although not very low, is on the lower side.
Taken together with your age, and although the nasal bone is clearly visible, it would be advisable to go for further testing to confirm or rule out chromosomal abnormalities.
I hope this helps.
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I am very sorry to hear of your loss. Loss of a baby can always be heartbreaking, especially when the cause for the event cannot be identified.
Two important effects of low PAPP-A are placental dysfunction and restricted fetal growth.
PAPP-A is produced by the placental cells called trophoblasts and help in growth of the placenta into the uterine wall. A low level indicates that the placenta has failed to invade the uterine muscular wall properly leading to placental dysfunction and this is associated with miscarriage, intrauterine growth restriction (IUGR) of the baby, pregnancy-induced hypertensive disorders, fetal death in utero, premature delivery etc.
While this fact will not help now, it should help you in your next pregnancy should you plan to go for one. Medicines like low dose aspirin can help dilate the blood vessels of the uterus and stimulate placentation. They should be started as soon as you get pregnant (miss a period).
I hope this helps. Once again, I would like to express my sympathy at your loss.