Hi, I am an American Board Certified Neurologist and I am very glad to help you with your health concerns.
Nuzak which is the brand name for Fluoxetine, which is usually used for the management of depression, or anxiety disorder or stress etc is overall a very safe med. And the usual maximum dose of this med is about 60 to 80 mg per day. So anything above this does can be considered as over dosing with Nuzak. Although above 80 mg is considered as overdose however the actual experience with this med shows that even very high doses of this med are tolerated reasonably well. In fact up to around 1500 mg this med is considered only minimally toxic. And doses above this may produce serious side effects including the possibility of seizures or even death some times.
The earliest side effects that are encountered during over dosing include restless ness, mild tremors or tremulousness, some increased anxiety, increased heart beats (tachycardia), drowsiness, nausea, vomiting or diarrhea etc. At higher doses of overdosing patient will start experiencing severe agitation, confusion etc. Seizures too occur typically at higher doses of overdosing. As mentioned above upto around 1500 mg is considered to be only “minimally toxic” on this med, but above this dose serious side effects start occurring including even death due to severe fatal irregular heart beats or severe life threatening seizures etc.
To summarize once again;
Up to around 60 – 80 mg/day is the recommended dose
Doses above 80 mg are considered as over dose
Although doses above 80 mg is considered as overdose, however up to around 1500 mg this med generally does not cause any serious or life threatening side effects, rather causes only minimal toxicity or minimal side effects.
Doses above 1500 mg overdosing is expected to cause serious and/or life threatening or fatal side effects.
The dose you have mentioned in one of your other questions at this site, that is around 240 mg is not expected to cause any life threatening side effects (as discussed earlier above too because up to around 1500 mg this med does not cause serious or life-threatening side effects). At these high doses (above 1500 mg overdosing death can occur rapidly if heart suddenly stops functioning, or if patient stops breathing suddenly.
Please let me know if you have any further questions; and if you feel you have received the answer to your question please rate me so that I can receive credit for the time and effort put by me in answering your question.