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The standard treatment should work. This includes 2 weeks of amoxicillin, clarithromycin and a proton-pump inhibitor like Nexium twice daily.
The "test-and-treat" strategy for H. pylori infection is a proven management strategy for most patients with uninvestigated dyspepsia or epigastric burning who have no “alarm features” (bleeding, anemia, early satiety, unexplained weight loss, progressive dysphagia, odynophagia, recurrent vomiting, family history of GI cancer, previous esophagogastric malignancy, etc).
In complicated cases, it is best to see a GI specialist. Sometimes scoping (EGD) is needed to visualize the esophagus and stomach and rule out a more serious underlying condition.