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Hi Randy, my name is***** problem will typically be caused by a faulty door lock actuator. The door lock and the actuator are sold as an assembly. If all other doors lock and unlock you should simply need to replace the lock with actuator for the driver's door. In some cases the actuator will seize up and prevent you from locking the door manually which appears to be what has happened in your case. The actuator retails for approximately $165 without the keyless go option. It's a 2 hour labor operation to replace the lock.
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