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Question practicing Psychiatrist only- I have been on Zoloft 5 years and on laxapro then pristique 3 years before that. I am now on a 50 mg dose which keeps me very even keeled. So two questions- Is Zoloft safe to continue on long term? I drink a couple of drinks probably once a week- is this ok? I know there's a warning not to drink but I thought that was simply because it intensifies the sedative effect.