Thanks for the inputs.
Well, i can suggest you some very good anti depressant medications in combination which are used to manage Depression which is difficult to treat. Some good examples are as mentioned below.
1) Effexor XR ( Venlafaxine extended release ) at dose of 37.5 - 75 mg / day + Remeron ( Mirtazapine ) at dose of 15-45 mg/ day.
2) Lexapro ( Escitalopram ) at dose of 10-20 mg/ day + Lamictal ( Lamotrigine ) at dose of 25-100 mg / day. + Modafinil / provigil at dose of 50-100 mg/ day
In addition to any one of these two drug combinations, you will have to seek CBT ( Cognitive Behavior Therapy ) as a specialized therapy from a clinical psychologist to learn coping skills and strategies.
-- If for some reason you try and fail to reap benefits from any of these options then i would suggest that you may discuss the option of ECT ( Electro-convulsive Therapy ) UNDER THE SUPERVISION OF A Psychiatrist , this is also called as Shock Therapy in colloquial terms and it is consdiered to be very effective and safe option for treating Intractable or treatment resistant depression.
-- rTMS ( Transcranial Magnetic Stimulation ) which comes as a recent advancement in terms of managing treatment resistant Depressive cases, where in through magnetic stimulation one tends to counter depression, it requires the supervision and guidance of a psychiatrist. Kindly see the link below to learn more about this choice of treatment.
So kindly all of these options with your GP and if possible involve a psychiatrist to take a decision on the treatment modality that you will like to choose from the list mentioned.
I hope this helps.
Wish you all the best.
Please kindly leave a POSITIVE RATING if you are satisfied with the answer.