This is Dr. David
Anhedonia is the inability to experience pleasure from activities usually found enjoyable
Dysthymia sometimes also called neurotic depression, dysthymic disorder, or chronic depression
for some patients, there is no cure of these conditions, but they can be treated.
it sounds like you have had treatment with zoloft SSRI agent.
or some patients with severe depression symptoms, additional of other medications such as seroquel or abilify can help your depression medications work better
ECT or elctroconulsive therapy can help some patients as well
has your doctor talked to you about these options?
what other questions do you have?
let me know if you have other questions.
but you are not willing to ask any further questions.
you want a cure for a condition where there is no cure.
we have nothing to do with Mayo Clinic here.