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Hello and thank you for using JustAnswer. I am very sorry if you are having these intensive depressive thoughts, I can understand how distressing this can be for you. If you are having thoughts of harming yourself than you have to go to the emergency room immediately to prevent you from making a mistake that you may regret later. May I ask, are you currently undergoing any form of therapy along with your Zoloft use? Also how long have you been on the medication and at what dose?