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Hello and thank you for using JustAnswer. May I ask, why did you decide to try to taper off your Klonopin? How long does the shaking last and does it occur in the day time at all?
Thank you for your response. You are definitely taking a high dose of the Klonopin and usually it should only be taken twice a day as it has a long half-life, so most people find taking it three times a day too sedating. The shaking in your sleep is most likely not a physical reaction to the Klonopin, but more of a psychological reaction in your unconscious mind that manifests while you sleep. Most likely your anxiety and worry about the Klonopin it self causes these reactions while you sleep...think of it like a nightmare as your unconscious mind gets overwhelmed by these fears and worries concerning your Klonopin use and your experience trying to taper off it. I would recommend seeing your psychiatrist before trying to taper off, but usually decreasing by .25mg every 2 weeks is a good and conservative tapering schedule to avoid withdrawal symptoms given the dose you are on and how long you have been taking this medication. It will be a long process, but if you are patient you can taper off this medication successfully.
It is possible that Vitamin B shots in themselves are causing the reaction and this is not an interaction with your Klonopin. There are no known interaction effects listed with Vitamin B and Klonopin.
I hope this answers your questions and gives you some guidance on this issue. Please let me know if you have any questions or concerns as I am happy to assist and support you regarding this issue.
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As I stated before the shaking at night is unlikely this is a physical reaction from trying to taper off the Klonopin as you would have other symptoms in the day time as well and they should have resolved by now. I think this is more of a psychological reaction of anxiety, worry, and fear that you have regarding the Klonopin use and basically you are waking up shaking from a nightmare as your unconscious mind is trying to deal with this anxiety and fear while you sleep.
Usually this will be temporary as you and your psychiatrist come up with a good plan to get off the Klonopin as that should put you at ease. You can also consider undergoing Cognitive Behavioral Therapy (CBT) for your anxiety and worry.