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Hello and thank you for your question. You are using the term "psychic" in your question which is an extrasensory perception to detect things that the normal senses cannot, such as read peoples minds, see the future, or converse with the dead. For this reasons the term "psychic" is not scientific at all and not involved with psychology or mental health, but more involved with alternative and pseudoscientific matters. So are you referring to psychic in this way or are you trying to use this word in another way that would be relevant to mental health?
In addition, brain inflammation should be discussed with a neurologist as that is a physical issue involved with the brain, not a mental health issue.
Well I just wanted to make sure I was understanding your question because some people do believe that psychic activity is real. What you are now talking about is mental/cognitive activity within the brain. So lets answer the questions that I can answer for you.
1. An individual's subconscious activity is affected by sedative medications to a degree because sedative medications can interfere with REM sleep and in REM sleep is where the greatest amount of subconscious and unconscious mind activity is established. The activity in the subconscious/unconscious mind could affect the conscious mind, but this will vary from person to person.
2. As I stated before inflammation of the brain is a neurological issues as any inflammation is going to be due to an infection or trauma, so it is not a mental health issue nor should it be treated as such. As for your psychic activity question, it does not make sense, so if you want to rephrase that without the use of "psychic activity" and without inflammation than I may be able to help you.
3. Inflammation of the brain will be treated by a neurologist using non-psychotropic medications or possibly through surgery depending on the location and severity.
EEG determine electrical activity within the brain and fMRI scans can help determine which parts of the brain are active during different situations (e.g. sleep, awake, psychosis, mood swings) or when presented with different stimuli (e.g. visual, auditory, smell, etc...). I agree that modern technology cannot detect all levels of brain activity, but that is because it has not been invented yet and because such activity has not yet been defined yet. I wish you all the best with your research and please let me know if you have any further questions or concerns :)