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Hello I believe I can help you with your question
The Deplin is a medical food meant to be used in conjunction with an antidepressant to help regulate the metabolic functions to lessen the symptoms of depression. In addition the Deplin is also calcium salt of the Methylfolate, so it is chemically different than pure Methylfolate
In addition most supplements have a fraction of the dosage Deplin has too, so that is why Deplin is far more effective than over the counter Methylfolate
The processing of this calcium salt in the Deplin improves the effectiveness of the antidepressant in the body
would the over the counter have any of the benefits?
Not really, very minimal and probably barely noticeable benefits if any
ok thank you