I'd like some information regarding the effects of some antidepressants that I'm taking. I'm currently on Wellbutrin 300 mg, Abilify 5 mg as well as Valdoxan 50 mg and Remeron 15 mg. When it comes to Valdoxan and Remeron I don't take them both every night. I noticed Valdoxan offers a more balanced 8 hour sleep while Remeron seems to front load 6 hours with deep sleep and REM, that's according to the Zeo sleep manager that I've been using. Remeron is actually more sedating at lower doses because from what I've read it also affects norepinephrine at higher doses which is more activating.
I was wondering if Abilify also has a similar counter intuitive effect, in that it's more activating at lower doses by affecting dopamine more and calming at higher doses by affecting serotonin more. It's more difficult than Remeron to notice a difference at different doses because of its longer half life as well as the fact that it's so expensive so I can't just take a higher dose and see what happens. What I want is the highest possible activating and motivating effect to get me through the day. Which dosage level would be the most ideal for this? I started Abiify at 1 mg and now that I'm at 5 mg I think it might be less activating. Was having more energy the first few days just an initial effect?
Also I want the opposite for my night medication. What dosages would you recommend for that?
There's also a second issue which is a bit embarrassing. I noticed that when I begun taking Abilify it caused a certain sexual side effect, specifically, premature ejaculation. I used to take Cymbalta which had the exact opposite effect, would it help with that? Maybe I could take apart the capsule and measure the pellets for a lower dose like 10 mg. Would it interact with my other medication in any bad way? The med cocktail I'm on now is by far the best I've ever been on so that's why I'm hesitant to mess with it. But if the problem persists I'll have to.
By the way, I've been diagnosed with dysthymia, major depression, ADHD, mild social anxiety and insomnia.