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Well, i will agree with you here that you should not directly switch over from lexapro to pristiq as these are two different class of drugs , so direct switching is not recommendable as this way you may develop ssri withdrawal side effects which are quite distressing..
So, i reckon the best safer way to switch over to pristiq is to first taper down the dose of lexapro by reducing the dose by 5 mg every 5 days till you reach 10 mg dose and then from there reduce the dose to 5 mg after 1 week and then stop the drug completely..
Only after stopping lexapro completely , shall you start on pristiq at 50 mg dose..
You see my opinion may be exactly opposite of what your doctor is saying but i say so because i know for a fact that the withdrawal side effects of lexapro when it is abruptly stopped are really distressing for the patient , so it is my honest advise to discuss this strategy with your doctor to carry out the switch over and anyways if 2-3 weeks wait helps you to have a safe switch over .
i hope you see reason in this..
I heard withdrawal from lexapro is very bad
what are the side effect of w/d?'
anxiety, electric shock sensations in the brain called as brain zaps, insomnia,
when you say reduce by 5mg, just take off 1/6 of each pill per day?
how are you taking 30 mg dose right now? is it a single tab
I shouldn't start Pristig at all while I'm weaning off of Lexapro? Yes, one tab
you got it right.
Lexapro was great the first 3 months
and then it stopped working and i got anxiety again
is that typical of these meds?
together if taken they may increase the risk of causing a life threatening emergency called as serotonin syndrome..
so avoid taking them together..
they are both not SSRIs?
the reviews of pristig are pretty good, but i'm guessing it's a new drug
it is typical of these meds to develop resistance / increased tolerance which reduces their efficacy..
that's not good,
lexaprp is ssri
this means that we all have to switch all the time
while pristiq is snri
not necessary ,
it's just finding the right match?
sometimes a drug remains effective for long enough duration to see you through the symptoms..
i'm afraid as i am weaning my anxiety will increase
because different body types react differently to different drugs..
can i do something about that?
weaning from lexapro, that is...i need to stay focused in my job
i'm afraid i will be too anxious if i'm in transition
ask your doctor to put you on klonopin 0.25 mg in the morning and 0.25 mg in the evening for 2-3 weeks so as to keep your anxiety away while this switch over is complete..
this drug will buy you time for the swtch over ..
should i be concerned that my internist thinks these are the same class of drugs?
thanks for the suggestion
i would imagine that this is typical of an internist
yes tell him that these are different class drugs..
they don't specialize
as i have mentioned above..
this has been helpful. do i get this chat emailed to me?
or should i copy and paste?
well this chat will be saved in your account here at Just answer which you can also copy and paste or print directly..
thank you very much, doctor
very helpful indeed.
Wish you all the best..
Do discuss this with your doctor and have a safe switch over..
take care and thank you
If the withdrawal side effects develop ( which is likely if the switch over is direct without tapering but not necessary to happen as some people may escape these withdrawal side effects despite such a switch over ) then these will not be dangerous but yes distressing and uncomfortable and they weill be self limiting and will subside within 2-4 weeks , so if you are prepared to endure these side effects then you shall go ahead with it.