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Dr. Vikas
Dr. Vikas, Psychiatrist
Category: Mental Health
Satisfied Customers: 2239
Experience:  MBBS ; M.D Psychiatry, MS. Health Informatics
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would 300mg quetapine nightly and 150 daily be ok to take

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my daughter has suffered for years since the birth of her second son who is now 12 she has now been diagnosed with bi polar she is on 300grm of quetiapine and has been told if down during the day take anorther150grm she is reluctant to take any more qutiapine because she drives daily doing school runs

Hello

The daily dose of Quetiapine in Bipolar disorder is from 400-800 mg per day so considering her diagnosis, 300 mg is a comparatively low dose and her symptoms can reappear later on if she continue this dose.

Now your concerns are also valid as Quetiapine is a very sedating medicine and patients may experience significant sedation with this medicine, however she has been taking this medicine for some time and it has been seen that sedation side effect can wear off over time.

Also sedation is not necessarily increased as the dose increased so an increase in dose can be worth trying. Just make sure that she is not driving on that very first day when she is taking this extra dose. If she does not feel sleepy by taking this extra 150 mg in the morning it can be continued as her doctor wants.

In case she feel sleepy, her doctor can also consider the option of adding a low dose of Aripiprazole (7.5/15 mg) in the morning instead of increasing the dose of Quetiapine. Aripiprazole is an activating mood stabilizer / antipsychotic, is very useful in Bipolar disorder and can be a very good option in her case.

I hope this helps, please feel free to discuss further if you have any related query.

Kind regards

Vikas
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