Sir with all due respect. I see a CRNP you are listed as an M.D. I feel that you are more qualified. If I was one of your patients and the same scenario existed from the BupropionXL what would you tell me as a patient? I felt no tightness in my throat or chest. There was NO swelling anywhere mouth, face, lips, or tongue. Just some patchy hives which faded on there own. i took the Benadryl for the itching on my hands and feet. I really need a better answer than the one you originally provided. I can get that answer for FREE from a simple phone call to the emergency room.