Thank you for your question. To answer your question directly, they are both SSRIs, but Lexapro also has an antianxiety component, whereas Zoloft is strictly for depression. However, since every one has different body type and chemistry, they work differently for people.
I am a 56 year old woman. I havae a famil hstory of depession and have sufferd with fairly mild recurrent deprssion since I was forty. I got sick inJuly with a whole range of symptoms from chest pain and shortness of breath, faintness, extreme ftigue and weakness After may tests, my doctors concluded that my symptoms were caused by psychological factors - depresion and anxiety. I am on 2 mg tabs of clonazepam twice a day and 100 mg of sertraline. I also started hormone replaement therapy two months ago. My anxiety and depression have improveved somewha but my Hormone Doctor says that Zoloft is the wrong medication for me. She says that Zoloft is out dated and that Lexapro would be better for treating "anxiety related depression in menopause." I would like to get off te clonazepam eventually and I suspect that that is what is controllong my anxiety. Is it possible that Lexapro wold control both anxiety and depression eventually letting me weanoff the clonazepam? She recommended a dose of 10 mg.
I apologize for the technical difficulties I am experiencing on my end. I will be switching to the Q&A format and continue this conversation.