Hi, I'd like to help you with your question.
Your friend sounds like she may be addicted to drugs and maybe alcohol. She may feel hyper and be unable to calm herself and instead of seeing her doctor to find a solution, she is self medicating. She could have ADHD or another disorder causing her to feel this way and she needs medication, but instead is using alcohol and pot, both depressants, to calm herself.
She could also have issues in her past and is using alcohol and drugs to cope with her pain. Many people who use have backgrounds of abuse and use so they do not have to feel their own pain about what they have been through. You mentioned that your friend is close to her family, but that does not exclude the possibility that someone abused her in childhood. Also, her relationships with men do not appear to be healthy. That may be a clue that something happened to her as a child.
Cocaine addiction is marked by significant weight loss, insomnia, increased activity, muscle jerks, and possible hallucinations. Feelings of paranoia and grandiosity are common with heavy use.
You can suggest to your friend that she get help. Seeing her doctor first may be easier. Some people are more willing to see a doctor before they will see a mental health professional. The doctor may be able to convince her to get help.
You can also try an intervention. Here is a link to tell you more about interventions:
Either way, your friend needs help. Try to be supportive as possible, but realize that she may refuse help until she hits bottom or ends up in a hospital where she can be cared for.
I hope this helps you,