Abilify has been on the market to short of time to really know for sure. IT took many years to see "poop out" in SSRI's. For certain types of OCD, I have seen similar drugs used with success to control the intrusive thought associated with OCD. It is not a type of drug that one would expect to "poop out". Dose may require adjustment and Abilify has less side effects than older medications used for same purpose. Enjoy the relief and expect continued success.