Antidepressants when given to a patient may induce hypomania, mania / bipolar
disorder which is sometimes associated with suicidal ideation. In this case, the usual strategy is to add
a mood stabilizer such as Lithium, Lamotrigine, any other atypical antipsychotic such as Abilify and / or discontinuation of the antidepressant in question.
Probably this happened to your daughter also. Every time your daughter was prescribed an antidepressant, her condition worsened and which improved by stopping that antidepressant and adding Lithium or abilify.
It appears to me that her current symptoms are very much suggestive of severe depression. Lithium is a mood stabilizer but it can't control the depressive symptoms and therefore a logical step should be to add a medicine / treatment modality which is able to control her depressive symptoms with suicidal tendency.
Usually, in patient suffering from depression with suicidal tendency Electro convulsive therapy (ECT) is a very good option and is very effective. Patients respond immediately to ECT in comparison to medicines.Electroconvulsive therapy (ECT)
If you don't want to consider the option of ECT, the other alternative could be to add Lamotrigine/ antidepressant along with Lithium.
Since she developed serious skin rash with Lamotrigine it can be left out so a combination of Antidepressant along with Lithium could be a good option.
It depends on her psychiatrist, which antidepressant he /she would like to add with Lithium but we usually prefer Wellbutrin (Bupropion) or Pristiq for this purpose.
You can discuss with her doctor about the options I have mentioned and hopefully she will get better very soon.
If you have any other query, please feel free to ask.
Wishing her a very early recovery and best of health in near future.
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