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Hi, I'd like to help you with your question.
Effexor should be taken with a full glass of water and with food. Also, take it at the same time each day. Effexor side effects can include nausea and loss of appetite so the food and water will help offset these side effects. Also, do not use alcohol while on this drug.
Be sure to allow 4 to 6 weeks before it reaches therapeutic levels in your body and begins to work effectively.
Let me know if I can help in any other way,Kate