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Thank you for trusting JustAnswer with your important question.
First, I looked up the research you mentioned, and it was a very small group of people (only 12). I would really like to see this done with a lot more people to be good science.
That being said, I have had many clients who have complained that generics did not work as well as, or as long as, the brand name medications.
Sometimes it is a difference in the client's body's ability to break down the medication the same way. Other times it really does seem to be a flaw in the manufacturing problem.
The generics are supposed to have the same active ingredients, but their quality can vary, and they may use inactive ingredients that affect how the medication is absorbed/used (such as colors, coatings, and other fillers to make the pill).
je told me the generics can be up to 20% difference and be continued the same
If you're not getting the results you used to get from the brand, then try going back. If you still don't get good results, it means your body either needs a higher dose or maybe it's become resistant to the medication and needs a different (or additional) antidepressant.
The 20% difference rule is to allow for those differences in mostly the inactive ingredients.
Good to know, thank you for your time